GATA4 and GATA6 are zinc-finger transcription factors that regulate specific genes involved in steroidogenesis. GATA6 reduction only improved basal and decreased with both vehicle and cAMP, and GATA4 reduction only lowered cAMP levels with cAMP. No changes in mRNA were observed LY-411575 IC50 with GATA reduction comparable to the control RNAi condition. Levels of insulin-like… Continue reading GATA4 and GATA6 are zinc-finger transcription factors that regulate specific genes