The transgenic (tg) expression of interleukin (IL)-4 under the control of a significant histocompatibility complex (MHC) class I promoter qualified prospects to B cell hyperactivity in mice, seen as a increased B cell surface MHC class CD23 and II expression, elevated responsiveness from the B cells to polyclonal ex vivo stimulation, and increased immunoglobulin (Ig)G1… Continue reading The transgenic (tg) expression of interleukin (IL)-4 under the control of